Rowe Researcher: Effects of mutants in the I-domain on Bacteriophage P22 coat protein stability and mature capsid structure

July 30, 2014

Fejiro Okifo conducting research.
Fejiro Okifo conducting research.

February 2014-Present: Effects of mutants in the I-domain on Bacteriophage P22 coat protein stability and mature capsid structure

By Fejiro Okifo, Kevin Robbins, Dr. Carol Teschke

Department of Molecular and Cell Biology, University of Connecticut, Storrs

As common as the rhinovirus that visits itself upon us every flu season and as insidious as the HIV virus that causes AIDS, viruses have been afflicting the human race since the dawn of time. And yet there is still much to discover about the mechanism by which they infect their hosts. (more…)

Fall 2014 Political Science Graduate Seminars

July 18, 2014

The political science department invites Honors students to consider taking one of the following graduate seminars. With your advisor’s approval, graduate courses may be included in your Honors Final Plan of Study for graduation. They also count toward your Honors participation requirements.

POLS 5460 COMPARATIVE SOCIAL POLICY
Lyle Scruggs

Social Policy is a large, interdisciplinary field drawing liberally from disciplines of political science, sociology, and economics. It encompasses everything from national public pension programs to neighborhood drug rehabilitation programs. In terms of resource commitment, it is the guts of modern government policy in wealthy countries, and is likely to become so (if it is not already) in emerging countries.

This course is a theoretical overview of comparative social policy, with an emphasis on contemporary research on the political economy of welfare states in Europe and North America. The field ranges from rather abstract theoretical and “macro” to the very practical “micro” aspects of individual case work. We will pay most attention to the theoretical and “macro” issues in this class. (Neighborhood and casework levels are usually emphasized in Schools of Social Work and Public Administration.)

POLS 5605 SEMINAR IN QUANTITATIVE METHODS OF POLITICAL SCIENCE
Prakash Kashwan

Introduction to the data analysis techniques most often used by political scientists. Requires no previous background in statistics.

Over the past several years that Professor Kashwan has taught this class, he has developed a ‘non-mathematical’ approach to introductory statistics. The focus of the class, instead is on helping students become adept at understanding and applying the tools of statistics to political and economic questions of the day. This approach facilitates quality student engagement in the group projects that students work on for the semester. The style and the contents of teaching have resonated with students, which is evident in anonymous student evaluations, such as the following comments:

“Quantitative terms and concepts were presented in a way that was easily understood by liberal arts students.”

“Professor Kashwan – YOU ARE SO POSITIVE! You have a great attitude, you keep the humor and morale up in class and you clearly care about the happiness and success of your students. You are my favorite professor for that reason.”

PSYC 3885-001: Special Topics: Community-Based Participatory Research in Obesity Prevention, I

Instructor: Amy Gorin

5 credit course. This course is intended to be taken as part of a year-long sequence; part II will be offered in Spring 2015.

This course provides a unique opportunity to study a complex health problem – obesity – from a social ecological perspective and to work with community partners to assist in the development, implementation, and evaluation of a statewide obesity prevention campaign using community-based participatory research methodology. Lectures focus on current obesity trends, causal factors of excessive weight, and the consequences of obesity. Community-based participatory research skills include focus groups, interviews, and environmental audits to develop an obesity prevention program that meets the needs of a diverse population. The course is designed for honors students and other advanced undergraduates with an interest in applied research, nutrition, physical activity, and health behavior change.

For more information about the course or the Obesity Prevention Learning Consortium, please contact Dr. Amy Gorin.

2014 Rowe Scholar: Ivan Navarro

July 17, 2014

Ivan Navarro
Ivan Navarro (Freshman)

Hailing from Bristol, CT, Ivan Navarro graduated from Bristol Central High School where he started a chess club in order to share his love of the game. A pre-pharmacy student at UConn, Ivan’s interest in a career in the health professions was significantly influenced by his mother, who is a CNA (Certified Nursing Assistant).

2014 Rowe Scholar: Jeremy Figueroa-Ortiz

July 14, 2014

Jeremy Figueroa-Ortiz
Jeremy Figueroa-Ortiz (Junior)

Jeremy Figueroa-Ortiz recently returned from a dental mission trip to the Galapagos Island of Isabella, where he, dental students, and dentists provided free dental care. An allied health sciences major with interests in dentistry and policy, Jeremy has also taken part in a clinically based pilot study called Project Good Oral Health, which focused on the oral health of geriatric communities and preventative health education. Jeremy is a bilingual (English and Spanish) graduate of Farmington High School who hails from New Britain, CT.

Rowe Researcher: Measuring Viral Titer to Analyze Transduction Efficiency in Induced Pluripotent Stem Cells

Spring 2011: Measuring Viral Titer to Analyze Transduction Efficiency in Induced Pluripotent Stem Cells

By Dr. X. Cindy Tian, Yong Tang, and Michael Tassavor

Stem cells have the ability to dramatically change the medical landscape, allowing regrowth and regeneration of tissues previously irreparable to modern science. Severe burns, spinal breakages, and muscle damage all can benefit, as well as more abstract diseases such as Parkinson’s, Multiple Sclerosis, and cancer. Until quite recently, however, sources for stem cells were limited to embryonic material.

In 2007, researchers managed to convert specialized adult cells to pluripotent stem cells capable of taking any somatic form in mice. This is highly useful in that it negates any need for embryonic stem cells in stem cell therapy, sidestepping legal and moral issues, as well as public outcry. Furthermore, it allows customized cells grown from the patient’s own cells, preventing immune rejection. Non-embryonic stem cells also have the benefit of allowing research to proceed with government grants, which, depending on the state and federal agencies involved, prohibit embryonic stem cell research. (more…)

Rowe Researcher: Investigating Propargyl-Linked Antifolates

Summer 2012-Spring 2014: Investigating Propargyl-Linked Antifolates in Inhibiting Bacterial and Fungal Dihydrofolate Reductase

By Joshua Andrade, Dr. Amy Anderson’s Lab, and Dr. Dennis Wright’s Lab

Antimicrobial agents have been invaluable in reducing illness and death associated with bacterial infection. However, over time, bacteria have evolved resistance to all major drug classes as a result of selective pressure. The advancement of new drug compounds is therefore vital.  The Anderson-Wright Lab has focused on developing potent and selective inhibitors of dihydrofolate reductase (DHFR), an enzyme key in cell proliferation and survival, in several pathogenic species.  The lab has found that a set of compounds, known as propargyl-linked antifolates, are DHFR inhibitors that are both biologically effective and have strong pharmacokinetic properties. (more…)

2014 Rowe Scholar: Kavisha Thakkar

Kavisha Thakkar
Kavisha Thakkar (Freshman)

Kavisha Thakkar is from Newington, CT but has traveled to 54 countries. She enjoys photography and travel and says that her experiences abroad have definitely played a role in her desire to pursue a career in medicine. In pursuit of this goal Kavisha has shadowed ophthalmologists at UConn Health and Veteran’s Hospital, and has conducted research on DNA at Hartford Hospital. She is now following a pre-med track and majoring in physiology and neurobiology at UConn. A graduate of Newington High School and the Greater Hartford Academy of Math and Science, Kavisha has taken part in several HCOP programs, including the Mini Medical Program, the High School Summer Research Program, and the Pre-College Enrichment Program.

2014 Rowe Scholar: Ornella Tempo

Ornella Tempo
Ornella Tempo (Junior)

Ornella Tempo is originally from Fusagasuga, Colombia but graduated from Wethersfield High School in Connecticut. Currently a chemical engineering major, her main academic interest lies in tissue engineering while her hobbies include swimming and painting. Ornella has had the opportunity to serve as student assistant to the Institutional Review Board, where she helps with instructor training, and as a research assistant at the Institute of Regenerative Engineering Laboratory. At the lab she has engaged in activities such as cell culture, creating microspheres, and microscopy imaging of microspheres.

2014 Rowe Scholar: John Odoom

Odoom,John
John Odoom (Freshman)

John Odoom loves playing basketball and is very proud of the fact that he didn’t quit but worked hard for two years in order to make Stamford High School’s varsity basketball team. Born in Ghana, Africa John now lives in Stamford, CT and is very interested in athletic training and physical therapy. As a basketball player he’s been able to observe the duties and demands of his team’s athletic trainer. He has also taken part in LEAD, a leadership program that provided him with the opportunity to tour Stamford Hospital.