[UConn Storrs]

Instructor: David J. Goldhamer

Prerequisite: BIOL 1107.
Recommended preparation: MCB 2400 (Human Genetics), MCB 2410 (Genetics), MCB 2210 (Cell Biology), or equivalents.

While this is not an Honors course, Prof. Goldhamer welcomes Honors students of all majors and would be happy to offer Honors conversions for interested students.

MCB 3219 emphasizes molecular, cellular, and genetic mechanisms that regulate animal embryonic development. At a fundamental level, animal development across species is remarkably similar. It is these similarities in gene regulatory networks, signaling mechanisms and cellular processes that will be emphasized. Yet, variations (sometimes enormous) on fundamental themes will also be highlighted to give a sense of the richness and diversity by which embryos of different species accomplish the monumental task of creating the next generation.

By emphasizing both classical and modern experimental approaches, you will gain an appreciation for the process of discovery and a conceptual framework by which to understand and approach the study of development, as well as other disciplines. Knowledge gained from the study of embryonic development is increasingly being applied in a clinical setting in the rapidly growing field of regenerative medicine. Thus, the practical value of understanding how embryos develop is enormous, and the relationship between embryology and clinical application will be a theme that runs throughout the course.

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