2016 Distinguished Alumni Award: Mark Romanoff

November 4, 2016

Dr. Romanoff has witnessed significant gains and challenges in the field of pain management since beginning his career as an anesthesiologist in 1987. The increased use of controlled opioid medications for non-malignant chronic pain has proved controversial, providing much needed aid to many individuals while fostering an epidemic of overdoses and addiction in both patients and society. Dr. Romanoff is on the committee on Narcotic Use and Diversion of the North Carolina Medical Society in North Carolina (NC), one of four states with the highest incidence of abuse. In 2007, Dr. Romanoff helped create a centralized database of all controlled medicines in NC. In addition, he has participated in several state-wide committees focusing on developing protocols and policies for the reporting and monitoring of narcotic use. In 2013, he was selected to participate in Project Lazarus–an educational and mentoring program set up by the NC Department of Health and Human Services. Dr. Romanoff’s continued lecturing, mentoring, and advising display his efforts to combat prescription drug abuse and ensure safe access to medication for those in need.

 

POLS 5505: Seminar in Public Law

October 24, 2016

Instructor: Kristin Kelly

With your advisor’s approval, graduate courses may be included in your Honors Final Plan of Study for graduation. They also count toward your Honors participation requirements.

This course focuses on the relationship between law and U.S. society.  In this seminar, law will be approached as both a political and a cultural institution that constitutes and is constituted by the society within which it operates.  The course is organized thematically and will include topics such as the definition of law, law’s violence, law and identity, feminist legal theory, law and social change, law and the “problem” of litigation, and law and social control.

The class will follow a seminar format and the majority of each class period will be devoted to discussing the assigned readings.  Participation in seminar discussions is therefore expected as a major component of your responsibilities in this class.

If you have questions about the course or if you would like to request a permission number to enroll please contact Professor Kristin Kelly (kkelly@uconn.edu).

ENGL 1616W-001: Major Works of English and American Literature

October 18, 2016

Topic: The Art of Storytelling

Instructor: Clare Costley King’oo

Prerequisite: ENGL 1010, 1011, or 2011

In this Honors course, designed primarily for non-English-majors, we will encounter several works judged to be literary masterpieces. Our aim will be to explore the art of imaginative story-telling over time, from the Middle Ages to the twentieth century (i.e., from Chaucer to Achebe). We will consider questions of narration, representation, genre, literary authority, intertextuality, and canonicity. Our discoveries will be the focus of our own rigorous writing practices, as we work on improving our argumentative and stylistic skills through a range of reports and essays (with revisions). Lively participation in class discussions will be expected and warmly encouraged.

CA 1, W.

ENGL 3318-001: Literature & Culture of the Third World – CHINA

October 17, 2016

Topic: Chinese Literature and Culture

Instructor: Patrick Hogan

Prerequisite: ENGL 1010, 1011, or 2011
This course may be repeated for credit with a change in topic.

The literary and cultural traditions of China are vast. Clearly, one cannot cover anything even approximating their range in a single course. In this class, we will focus on a few elements of Chinese tradition, exploring them in greater detail. Specifically, the course will begin with a careful reading of Confucius with perhaps some reference to Laotze and/or Mencius. We will then work through some Chinese lyric poems, principally following Cai Zong-qi’s How to Read Chinese Poetry. Some of this poetry extends back to the ancient beginnings of Chinese literary tradition. Following this, we will treat a collection of Yuan drama (13th-14th centuries C.E.), focusing on the relation of the works to historical concerns (e.g., Mongol domination and Chinese national identity). After this, we will consider some prose work. Depending on what is available, this may be the first volume of Cao Xueqin’s Story of the Stone (a.k.a., Dream of the Red Chamber, 18th century) or perhaps some popular story, such as the often retold tale of “the butterfly lovers,” Liang Shanbo and Zhu Yingtai. The final section of the course will treat one or two works of recent Chinese cinema (e.g., Lu Chuan’s Nanjing! Nanjing!), considering both their thematic concerns and their formal techniques. Midterm, final, short written responses to some of the readings, class presentations.

CA 4-Int.

ENGL 2401-002: Poetry

Instructor: Yohei Igarashi

Prerequisite: ENGL 1010, 1011, or 2011

This course is a beginner’s guide to reading poetry, organized around the study of canonical or “classic” British poems. Along the way, the course introduces elements of poetic form, rhetorical and literary terms, poetic genres, and questions about the status of poetic discourse in society. Assignments include a shorter and a longer paper, in addition to a midterm and final.

CA 1

PSYC 3201-002: Animal Behavior

October 14, 2016

Instructor: David B. Miller

Prerequisites: BIOL 1102 or 1107; PSYC 1100

PSYC 3201 ANIMAL BEHAVIOR is an overview of the scientific study of animal behavior covering a broad range of topics, including evolution, adaptation, domestication, mating, communication, development, ethological concepts, and much more. The course is constructed around many examples from the scientific literature on a wide range of species. This is actually a “hybrid” course, in that 90% of the material is available day and night via streaming screencast videos. Around 8 in-class sessions allow for the presentation of additional content that is not contained in the screencasts, and around 6 in-class sessions are devoted to questions and answers. This is a combined class, with 185 seats open to all students (who register in Section 001) and 15 seats reserved for Honors students (who register in Section 002 for automatic Honors credit). Honors students meet once weekly for around an hour for a discussion session. The instructor is Professor David B. Miller, of the Department of Psychological Sciences, who has an extensive background in field and laboratory animal behavior research, primarily on birds.

MATH 3094: Undergraduate Seminar – Quiver Representations

October 3, 2016

Instructor: Prof. Ralf Schiffler

Students with an interest in Algebra and Combinatorics may be interested in this Honors seminar. Appropriate for any junior or senior with substantial mathematical background and interest, not just math majors.

A quiver is an oriented graph. A quiver representation is a collection of vector spaces and linear maps; one vector space V_i for each vertex i of the quiver and one linear map f_{ij} from V_i to V_j for each arrow i–>j of the quiver.

The complexity of different representations depends on the quiver. For some (few) quivers we can explicitly write down a finite number of representations such that any representation of the quiver can be constructed from our finite list by taking direct sums and using isomorphisms.  In these cases our finite list can be constructed combinatorially in the so-called Auslander-Reiten quiver.

We will study the properties of quiver representations, and see how to compute the Auslander-Reiten quiver in specific examples, using algebraic methods as well as combinatorial methods for example triangulations of polygons.

Contact Prof. Schiffler with any questions or to request a permission number.

Rowe Researcher: Understanding the Role of SR-B1

September 12, 2016

Understanding the Role of SR-B1 in Lipid Metabolism and Inflammation

Summer 2016

Investigators: Christopher Blesso, Christina Jiang

SR-B1 is an HDL receptor that has a role in cholesterol exchange and the initiation of intracellular signaling cascades involved in lipid metabolism. SR-B1 is highly expressed in the liver, but its function has not been fully determined in adipocytes, which is the aim of this project. Cholesterol imbalance can result in disease states such as atherosclerosis, so the study of this HDL receptor can be implicated in disease prevention.

The aim of the research was to perform successful knockdown in 3T3-L1 adipocytes by using siRNA (scramble, cyclophilin, SR-B1); determine gene expression of SR-B1 and cyclophilin to confirm knockdown; determine inflammatory response of adipose by introducing LPS or macrophage-conditioned media to cells. After treating the cells with the appropriate reagents, RNA was isolated, cDNA was synthesized, and PCR was conducted to confirm knockdown. There was a 40% knockdown in cyclophilin when treated with cyclophilin siRNA and insignificant knockdown with SR-B1 knockdown. There is about a 60-70% knockdown of SR-B1 in adipocytes treated with SR-B1 siRNA, indicating that the knockdown was successful. In the presence of macrophages, there is about a 40% knockdown of SR-B1. In the presence of LPS, there is also about a 40% knockdown of SR-B1. These successful gene knockdowns provide evidence to continue on with the experiment.

Rowe Researcher: Drug Treatment for Depression

Shanicka Reynolds
Shanicka Reynolds presenting her research at Frontiers in Undergraduate Research

 

Drug Treatment for Depression: Deprenyl’s Effect on Motivation, Effort and Behavior

2015-2016

Investigator: Shanicka Reynolds

Depression is more than a feeling of sadness. It can progress into a disabling disease that degrades mental, physical, and social health. One of the most debilitating symptoms of depression is a decrease in motivational behavior. Motivational symptoms such as fatigue and anergia are difficult to treat and many of the existing antidepressants do not effectively treat motivational symptoms. This project will focus on the MAO-B inhibitor drug, deprenyl. The goal is to provide a more detailed characterization of the motivational effects of deprenyl through experimentation. Successful increase of motivational behavior using deprenyl will not only benefit patients suffering from depression, but will help patients of various disorders such as Parkinson’s where depression can be a side effect of their disease.