
Spring 2012: Social Interaction and Anxiety in Mutant BXD29 Mice
By A.C.Bonet1 , D.T.Truong2 , R.H. Fitch, PhD1
The purpose of this research was to observe anxiety and social interaction in the BXD29 mice strain. BXD29/Ty -wild type and BXD29-Tlr4lps-2J/J -mutant mice have never been tested for social interaction or anxiety related behaviors, thus this research offers a preliminary observation of the behaviors. The BXD29-Tlr4lps-2J/J mice have subcortical heterotopias formed by neurons destined for layers 2-4 of the neocortex as well as partial callosal agenesis. Continue reading